--- title: "Lipidomics" lang: en url: https://www.gereallife.com/en/services/lipidomics.html canonical: https://www.gereallife.com/en/services/lipidomics.html entity: Shanghai Gereallife Biotech Co., Ltd updated: 2026-11-02 --- # Lipidomics Untargeted Lipidomics — 47 Lipid Classes Covered Lipidomics systematically profiles and quantifies lipid molecules in samples. Lipids are the major constituents of cell membranes and are involved in energy storage, signal transduction and inflammation regulation; abnormalities in lipid composition and metabolism are closely linked to metabolic and cardiovascular diseases, cancer and neurodegeneration, making lipidomics a key entry point for mechanistic research and biomarker discovery. Using an untargeted strategy, a single injection delivers a panoramic scan of the lipidome, covering the 47 lipid classes listed below (glycerophospholipids, sphingolipids, glycerolipids, fatty acyls, sterol esters and their subclasses) — over 50,000 lipid molecules. 47 Lipid Classes Covered LIPID CLASSES 50,000+ Lipid Molecules LIPID MOLECULES Single Injection Full Scan SINGLE-INJECTION SCAN ## Lipid Class List (47 Classes) LIPID CLASS LIST Broad lipid coverage: the 47 lipid classes covered by this service — and the nomenclature used in reports — follow the LIPID MAPS classification system; the largest public lipid database has curated over 50,000 unique lipid structures. Extended analysis: the lipidomics cloud workflow is available on the OmicsHub platform — upload a matrix table to one-click reproduce QC, lipid composition, carbon-chain structure, differential screening and class-enrichment analyses, with report figures interactively adjustable in the cloud. ## Bioinformatics Analyses (8 Lipid-Specific Modules) BIOINFORMATIC MODULES | Module | Core Methods & Metrics | Key Outputs | | --- | --- | --- | | Lipid Composition | Hierarchical treemap of lipid classes (main class → subclass); stacked bar charts of relative class abundance per group; intergroup boxplots of the top-12 lipid classes with differential tests | Classification treemaps, stacked abundance plots, boxplots, class statistics tables | | Carbon-Chain Structure | Bubble plots of chain length vs. unsaturation; count heatmaps of major lipid classes × total carbon number; stacked bar charts of saturation composition for major classes | Chain bubble plots, count heatmaps, saturation composition plots and statistics tables | | Acyl Chains & Ether Lipids | Acyl-chain composition analysis (Top 15); class-distribution analysis of ether lipids (O- / P-) | Acyl-chain bar charts, ether-lipid distribution plots and statistics tables | | Differential Lipid Screening | Volcano plots and class-colored versions; FC + p threshold screening; strategy auto-switches between VIP + P and FC + P based on permutation-test results | Volcano plots (incl. classified), differential lipid lists | | Differential Lipid Abundance | Hierarchical clustering; complex heatmap of top-50 significant lipids; abundance analysis; correlation and Z-score analyses of top-10 up/down-regulated lipids | Cluster heatmaps, complex heatmaps, correlation and Z-score plots | | Lipid Class Enrichment | Fisher's exact test answers whether differential lipids concentrate in specific classes; carbon-chain distribution comparison of differential lipids | Enrichment result tables, chain-distribution comparison plots | | Biomarker Screening | Per-lipid ROC curves and AUC ranking to assess diagnostic/subtyping performance (performed when each group has ≥5 samples); Venn diagrams of differential lipids across comparisons | ROC plots, AUC ranking tables, Venn diagrams | | Nomenclature & Data Tables | Cross-reference of lipid class abbreviations and full names; explanation of the "carbon number : double-bond number" nomenclature | Classification cross-reference tables, full lipid statistics and screening result tables | ## Example Results SELECTED FIGURES FROM ACTUAL REPORTS Lipid Class Treemap Main classes (Glycerophospholipids / Sphingolipids / Glycerolipids / Fatty Acyls) and subclass composition, sized by detected lipid counts. Stacked Bar Chart of Class Abundance Relative class-abundance composition per group and intergroup differences. Intergroup Class Boxplots (Top 12) Distribution boxplots of the 12 most abundant lipid classes across groups. Chain Length vs. Unsaturation Bubble Plot Bubble size encodes lipid counts, showing distributions of chain length and unsaturation. Class × Total-Carbon Count Heatmap Heatmap of lipid counts for major classes at each total-carbon-number level. Acyl-Chain Composition Bar Chart (Top 15) Composition of the 15 most abundant acyl chains. ## Applications APPLICATIONS Lipid-Metabolism Disorders Membrane Composition & Function Lipid Biomarker Discovery Nutrition & Lipid Metabolism Skin / Neural Lipid Research ## FAQ FAQ How long does a Lipidomics project take? Mature targeted panels typically take 1-3 weeks; untargeted projects take 2-4 weeks (counted from sample receipt and QC approval). The exact timeline is confirmed in writing before project start, and progress is trackable on the OmicsHub cloud platform. What if my sample amount is below the recommendation? Please do not dilute your samples. Low-input samples can often be accommodated by adjusting the preparation workflow — tell us the actual amount and our technical team will assess feasibility and note adjustments in the study plan. Can I add targets to an existing panel? Yes. Mature panels support on-demand additions; novel analytes outside the list can be implemented through custom method development (requires standards and extra validation time) — see our Custom Targeted Metabolomics service. What samples do you need for Lipidomics? Serum/plasma ≥100 μL (fasting, no haemolysis), tissue ≥50 mg (snap-frozen), cells ≥1×10⁶ (medium washed off), urine ≥200 μL. Keep fasting time consistent, aliquot into single-use volumes and avoid freeze–thaw. Full guidance: Technical Resources → Sample Guide . ## Related Services RELATED SERVICES ### Metabolic Flux & Isotope Tracing Metabolic Flux & Isotope Tracing ### Targeted Metabolomics Targeted Metabolomics ### Environmental Exposomics Environmental Exposomics Delivery timing: sample shipping, customs declaration and similar steps may extend turnaround; actual project timelines prevail. ## Request a Quote or Study Design Tell us about your project — we reply within one business day (free assessment) Name Organization Phone or WeChat Service of interest Sample type, number of samples and aims (optional) Submit Used only for this enquiry; never shared. ## Start Your Multi-omics Project Free study design · Interactive execution · In-depth data interpretation HOTLINE 400-660-8826 EMAIL market@gereallife.com Official Channels OFFICIAL CHANNELS Official Account WECHAT OFFICIAL ACCOUNT WeChat Service CUSTOMER SERVICE Xiaohongshu XIAOHONGSHU Call us： 400-660-8826 Scan to chat on WeChat